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wikipedia.org
https://en.m.wikipedia.org/wiki/Monoclonal_antibod…
Monoclonal antibody - Wikipedia
A monoclonal antibody (mAb, more rarely called moAb) is an antibody produced from a cell lineage made by cloning a unique white blood cell. All subsequent antibodies derived this way trace back to a unique parent cell.
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drugs.com
https://www.drugs.com/medical-answers/what-monoclo…
What are Monoclonal Antibodies and how do they work? - Drugs.com
The mAb (ibritumomab) delivers a radioactive substance (Yttrium-90) directly to cancer cells. Another example is Kadcyla, an mAb that is attached to a chemotherapy drug.
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clevelandclinic.org
https://my.clevelandclinic.org/health/treatments/2…
Monoclonal Antibodies: Definition & How Treatment Works
The generic names of the products often include the letters “mab” at the end of the name. What is the difference between monoclonal antibodies and polyclonal antibodies?
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cancer.org
https://www.cancer.org/cancer/managing-cancer/trea…
Monoclonal Antibodies and Their Side Effects - American Cancer Society
Bevacizumab (Avastin) is an mAb that targets a protein called VEGF that affects tumor blood vessel growth. It can cause side effects such as high blood pressure, bleeding, poor wound healing, blood clots, and kidney damage.
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verywellhealth.com
https://www.verywellhealth.com/monoclonal-antibody…
Monoclonal Antibodies: How They Work, Uses, Side Effects
A monoclonal antibody (mAb) is a type of immune protein produced in a lab that binds to a specific protein on a cell called an antigen. As with naturally occurring antibodies, monoclonal antibodies stimulate the immune system to act against disease-causing agents. 1
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medicinenet.com
https://www.medicinenet.com/monoclonal_antibodies/…
Monoclonal Antibodies: Uses, Types, Side Effects & COVID-19
Minnesota Dept. of Health. "COVID-19 Medications." Oct. 12, 2022. https://www.health.state.mn.us/diseases/coronavirus/meds.html#mab U.S. Food & Drug Administration. "Coronavirus (COVID-19) Update: FDA Authorizes New Monoclonal Antibody for Treatment of COVID-19 that Retains Activity Against Omicron Variant."
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nih.gov
https://pubmed.ncbi.nlm.nih.gov/34283484/
Understanding How Monoclonal Antibodies Work - PubMed
The nomenclature of mAbs depends on the origin of each respective mAb. Common suffixes include -omab, -ximab, -zumab, and -umab, representing murine, chimeric, humanized, and human agents, respectively.
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mdpi.com
https://www.mdpi.com/2227-9059/13/8/1962
Monoclonal Antibodies (mAbs) and Proteins: The Biologic Drugs ... - MDPI
According to the FDA, axalitimab is a humanized mAb used to treat children and adults with chronic graft-versus-host disease (GVHD), a complication that can occur after receiving a bone marrow or stem cell transplant from a donor.
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usp.org
https://qualitymatters.usp.org/why-mabs-matter
Why mAbs Matter | Quality Matters | U.S. Pharmacopeia Blog
What exactly are mAb drugs and how do they work? Read on to learn about monoclonal antibodies and why they’re so important in healthcare. What are antibodies? To understand monoclonal antibody drugs, it’s necessary to first know a little about how antibodies work in the body’s immune system.
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synapseforges.com
https://synapseforges.com/articles/understanding-m…
Understanding Mab Drugs: Mechanisms and Impact
The first mAb approved for human use was muromonab-CD3 in 1986, targeting T cells during transplant procedures. Since then, numerous mAbs have been developed, revolutionizing treatments. Today, there are over 100 mAbs on the market, with new ones continually in development as research expands.