Greencastle is a city in Greencastle Township, Putnam County, Indiana, United States, and the county seat of Putnam County. It is located ne…Greencastle is a city in Greencastle Township, Putnam County, Indiana, United States, and the county seat of Putnam County. It is located near Interstate 70 approximately halfway between Terre Haute and Indianapolis in the west-central portion of the state. The city is the home of DePauw University. The population was 9,820 at the 2020 census.
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