Impact of CTNNB1 alterations on outcomes in patients with hepatocellular carcinoma (HCC). Efficacy and safety of envafolimab plus lenvatinib combined with TACE in initially unresectable hepatocellular ...
Concordance between cfDNA and tumor NGS is high for key mutations for important genes like TERT, TP53, and CTNNB1, indicating cfDNA can accurately reflect the tumor's genetic landscape. While ...
The pre-RFA blood HCC signature developed in the present study, which considers the blood levels of DCP (≥40 mAU/mL) and the cfDNA mutation score generated from cfDNA mutations in TP53, CTNNB1 and the ...
TOKYO, Feb. 7, 2024 /PRNewswire/ -- SMC Laboratories, Inc. ("SMC Laboratories"), a non-clinical contract research organization (CRO) that provides consulting and contract services for pharmacology ...
A study published in Chinese Medical Journal reveals potential of methotrexate to treat liver cancer
The study provides evidence suggesting that this widely used chemotherapeutic drug could be repurposed for treating a subtype of hepatocellular carcinoma Liver cancer is one of the most prevalent and ...
Researchers at the University of Oslo and Oslo University Hospital have developed a promising new immunotherapy targeting the CTNNB1 gene mutation associated with various aggressive cancers like lung ...
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