MSK researchers are shedding new light on G-quadruplexes, a type of secondary DNA structure that can cause DNA replication to stall. The structures are a potential therapeutic target in cancer. Image ...

Researchers have shown for the first time how Merkel cell polyomavirus (MCV), which causes an aggressive skin cancer called Merkel cell carcinoma, initiates DNA replication in host cells. University ...

Researchers at Baylor College of Medicine have discovered that certain p53 mutants hijack the DNA replication machinery causing it to fire ...

Cellular traffic jams inside a fruit fly embryo might sound like a minor detail, but new work suggests they help flip a ...

This transcript has been edited for clarity. For more episodes, download the Medscape app or subscribe to the podcast on Apple Podcasts, Spotify, or your preferred podcast provider. Dr Liu is a ...

Recent research has shed light on the complex processes that cells use to maintain the quality of mitochondrial DNA (mtDNA) ...

The University of Wisconsin’s Lim Lab has identified the cause of chromosome instability associated with a range of genetic ...

Cryo-EM revealed HIV-1 integrase’s distinct structures as it shifts between its two roles of DNA integration and RNA-binding.

Researchers discovered that embryos must clear maternal mRNAs to develop properly. When cleanup fails, it causes aberrant ...