Northwestern Medicine scientists have uncovered a surprising link between a tiny cellular engine and the way cancer cells ...

The protein UBR7 acts as a histone chaperone, regulating histone re-deposition at specific sites during DNA replication, according a recent study published in The EMBO Journal. This protein was ...

The University of Wisconsin’s Lim Lab has identified the cause of chromosome instability associated with a range of genetic ...

The tight wrapping of genomic DNA around nucleosomes in the cell nucleus makes it unavailable for gene expression. A team of Ludwig-Maximilians-Universitaet (LMU) in Munich now describes a mechanism ...

Colorado State University has identified an alternate method to study changes during the DNA replication process in lab settings using genetically modified yeast Researchers at Colorado State ...

SAN DIEGO--(BUSINESS WIRE)--Boundless Bio, a next-generation precision oncology company developing innovative therapeutics directed against extrachromosomal DNA (ecDNA) in oncogene amplified cancers, ...

MSK researchers are shedding new light on G-quadruplexes, a type of secondary DNA structure that can cause DNA replication to stall. The structures are a potential therapeutic target in cancer. Image ...

Researchers from Karolinska Institutet have discovered how mammalian cells prevent the gradual buildup of harmful mutations ...

Researchers have discovered the structure of the FACT protein -- a mysterious protein central to the functioning of DNA. It's long been known that the proteins that package DNA, like students at a ...

Hydrogels are polymeric materials with three-dimensional network structures containing large amounts of water. They serve as sustained-release drug delivery systems as they can encapsulate various ...

Dr. Roger L. McMacken Jr., the former chair of biochemistry and molecular biology at the Johns Hopkins Bloomberg School of Public Health who was an expert on DNA replication, died of a brain tumor Dec ...