Researchers have mapped the spatial distribution of around 700 long non-coding RNAs, otherwise known as lncRNAs, in the testes. The team discovered much higher levels of lncRNAs in the testes than had ...

“There is strong debate in the scientific community on whether the thousands of long non-coding RNAs generated from our genomes are functional or simply byproducts of a noisy transcriptional machinery ...

Genes contain instructions for making proteins, and a central dogma of biology is that this information flows from DNA to RNA to proteins. But only two percent of the human genome actually encodes ...

Schematic representation summarising MASLD-associated long non-coding RNAs (lncRNAs) and their relevant targets in hepatocytes: human leukocyte antigen (HLA) complex group 18 (HCG18), nuclear enriched ...

What keeps our cells the right size? Scientists have long puzzled over this fundamental question, since cells that are too ...

Among the large, diverse set of mammalian long noncoding RNAs (lncRNAs), long noncoding primary microRNAs (lnc-pri-miRNAs) are those that host miRNAs. Whether lnc-pri-miRNA loci have important ...

Originally classified as ‘junk DNA’, genomic regions which are transcribed into RNAs that do not serve as template for protein production have attracted increasing attention in the last two decades.

The study shows that a long non-coding RNA called CISTR-ACT acts as a master regulator of cell size, influencing how large or ...

What keeps our cells the right size? Scientists have long puzzled over this fundamental question, since cells that are too large or too small are linked to many diseases.

SickKids researchers discovered that a long non-coding RNA, CISTR-ACT, directly regulates cell size. Using gene-editing tools ...