Tokyo, Japan – Researchers from Tokyo Metropolitan University have been studying DNA repair by homologous recombination, where the RecA protein repairs breaks in double-stranded DNA by incorporating a ...
Precision gene editing is crucial for treating genetic diseases, as it enables targeted correction of specific mutations. A Korean research team has become the first in the world to significantly ...
Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, No. 4 (Feb. 19, 2002), pp. 2100-2105 (6 pages) Integration of foreign DNA was observed in the Gram-positive ...
This is a preview. Log in through your library . Abstract The modification of an endogenous gene into a designed sequence by homologous recombination, termed gene targeting (GT), has broad ...
New hope for advanced prostate cancer patients, with promising new drug combo that targets genes, such as BRCA1, BRCA2, CHEK2 ...
As chromosomes go, X and Y make an unlikely pair. The X is large and contains thousands of genes critical for life. The Y, by contrast, is little more than a nub. Its main purpose is to provide the ...
Homologous recombination deficiency (HRD) is a well-described phenotype of some prostate cancers; however, current biomarkers for HRD are imperfect and rely on detection of single gene alterations in ...
Two articles detail how human RecQ helicases regulate homologous recombination and protect genome stability. Taken together, these papers lend new insight into the molecular function of human RecQ ...
A recent study, undertaken by researchers at the Tokyo Metropolitan University and the Tokyo Metropolitan Institute of Medical Science (both Japan), unravels key steps in the process of homologous ...
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