Not long after nearly losing a fumble on a sack, Mac Jones finally unravels for the 49ers, tossing a deep pick to Jamel Dean that just might seal a home victory for Tampa Bay, which is getting heroic stuff from its own gunslinger in Baker Mayfield:

After Sunday's game, Jones said playing through injuries is in the team's DNA. But you have to wonder how long that DNA is sustainable.

Baker Mayfield tossed two touchdowns to help lead the Tampa Bay Buccaneers over the San Francisco in a battle of one loss teams from Raymond James Stadium.

One of Jones' favorite targets last week was Kendrick Bourne, who was his teammate on the New England Patriots from 2021 to 2023. Bourne said he noticed a difference between Jones the Patriot and Jones the 49er.

Each Jets loss gets them closer to Justin Fields' replacement. And, hey, Brock Purdy doesn't have to worry about a QB batter, right?

Teams across the NFL are dealing with injury concerns at quarterback. Here's the latest for multiple teams this week.

Jones made it clear that he still views Brock Purdy as the starter, and shared his approach to the 49ers' season moving forward.

The Los Angeles Rams learned a lot about themselves in their divisional home loss to the San Francisco 49ers in Week 5.

Defensive lineman Jordan Elliott blocked Joshua Karty’s extra point attempt that would’ve given the Rams a one-point lead in the fourth quarter. Later in the final period, defensive lineman Alfred Collins stripped running back Kyren Williams as the running back was about to cross the goal line for a go-ahead touchdown.

Sam Darnold's remarkable journey continues its climb in 2025. That includes a firefight against the only quarterback drafted ahead of him in 2018.

San Francisco 49ers quarterback Mac Jones fires pass to tight end Jake Tonges for a 16-yard gain against the Tampa Bay Buccaneers.