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Tampa Bay Buccaneers vs Los Angeles Rams picks, predictions, win probabilities for NFL Week 12 Sunday Night Football game on Nov. 23. Who will win?
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Week 12 NFL odds, picks, predictions: Our 12 NFL best bets, including a play in Cowboys-Eagles
Our NFL handicapping team of Ed Feng, Michael Fiddle and Matt Jacob combine to give their best bets for Week 12 of the NFL season. Odds courtesy of BetMGM and are subject to change.
While Detroit has struggled in outdoor environments, the Lions are a juggernaut at home on offense. They should be able to rebound from a poor showing in Week 11 against the Giants, who are tied for 29th in points allowed per game at 27.3. Detroit is averaging 29.2 points per game, which is tied for fourth-best in the NFL.
The Saints have converted a league-low 38.5% of their red zone trips into touchdowns and one of the lowest scoring first quarter and first half teams. It won’t take much for Cousins and Bijan Robinson to be able to put up 20 points in order to win to this game. I like Atlanta +2.5 down to +1.
The Chiefs' recent offensive lethargy is of growing concern to fans in Kansas City. Quarterback Patrick Mahomes has been off-form, and head coach Andy Reid has seemingly abandoned the ground game. With running back Isiah Pacheco out on Sunday, Mahomes is expected to continue airing it out with little concern for offensive variety.
The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 12 on a 48-33 run on top-rated picks dating back to 2024. Anybody following its NFL betting picks at sportsbooks and on betting sites could have seen strong returns.
The Jacksonville Jaguars play the Arizona Cardinals in Week 12 of the 2025 NFL season. Who wins? See our predictions and picks, plus game odds.
The Patriots look to move to a 10-2 record today against the struggling Bengals. Our Patriots vs. Bengals expert predictions highlight the best betting picks for the AFC clash.
Looking for an anytime touchdown scorer for Sunday’s action? The SI Betting team has you covered, as NFL betting insider Iain MacMillan and managing editor Pete
The decision thrusts Mason Rudolph into the starting lineup. He's provided steady play in the past. Most notably in 2023, Rudolph went from QB3 on the depth chart to starter, leading a surprising three-game winning streak to qualify for the playoffs.
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