Researchers develop a novel reporting system called the “EndoMT reporter endothelial cells” or EMRECs, to visualize the intermediate phases of EndoMT. Using RNA-sequencing and gene expression analyses ...

Years of experiments and databases filled with RNA-seq results belie the simple reality that, until fairly recently, it was impossible to analyze RNA directly. The RNA-seq studies performed with ...

Researchers have visualized how a large RNA molecule assembles itself into a functional machine. RNA is a central biological macromolecule, now widely harnessed in medicine and nanotechnology. Like ...

Eight years ago, 10x Genomics launched the first commercially available single-cell RNA sequencing (scRNA-seq) product for the company’s flagship instrument, the 10x Chromium. (This occurred one year ...

RNA sequencing has emerged as a powerful supplement to DNA sequencing for Mendelian disease diagnosis, but clinical translation of diagnostic RNA-seq has not been widely achieved. Researchers at ...

RNA sequencing (RNA-seq) is a powerful tool in diagnosing Mendelian disorders, but the optimized sequencing depth for this technology has not yet been determined. In a new study published in the ...