The assembly of a bipolar microtubule-based spindle is crucial for the accurate and timely segregation of the chromosomes into the two daughter cells during mitosis. Three microtubule nucleation ...
The attachment of sister kinetochores to microtubules from opposite spindle poles is necessary for accurate chromosome segregation during cell division. Unattached kinetochores activate the cell-cycle ...
Robert Blackwell, Christopher Edelmaier, Oliver Sweezy-Schindler, Adam Lamson, Zachary Gergely, Eileen O’Toole, Ammon Crapo, Loren Hough, J. Richard McIntosh ...
Takashi Hotta, Zhaosheng Kong, Chin-Min Kimmy Ho, Cui Jing Tracy Zeng, Tetsuya Horio, Sophia Fong, Trang Vuong, Yuh-Ru Julie Lee, Bo Liu The Plant Cell, Vol. 24, No. 4 (APRIL 2012), pp. 1494-1509 (16 ...
Cell division is essential to the propagation of life. During cell division, mitotic spindles segregate duplicated chromosomes with high fidelity. Spindle structure depends on the proper polar ...
Production of Ran-guanosine triphosphate (GTP) around chromosomes induces local nucleation and plus end stabilization of microtubules (MTs). The nuclear protein TPX2 is required for RanGTP-dependent ...
Modern CNC machine tools work under increasingly diverse cutting conditions. They must handle workpieces of various sizes and materials, and produce good surface finishes while operating at ever ...
Balanced toolholder assemblies pay dividends in longer spindle and tool life and, especially, in greater metal removal rates at all cutting speeds. Photo courtesy Emuge Corp Modern milling machines ...
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