Conan O'Brien's final show as host of "The Tonight Show" features Tom Hanks and Will Ferrell, who had been guests on his first two shows, along with a variety of surprise guests.

Conan O'Brien has reason to smile after his debut as "Tonight" show host. His first Nielsen Media Research report card showed a 7.1 rating and 17 audience share in the nation's biggest media markets.

O'Brien left NBC in 2010 after the network wanted to bump "The Tonight Show" to 12:05 a.m. to make room for Jay Leno. Does time — and a new host — heal all wounds? Fourteen years after Conan O'Brien ...

In a few hours, Conan O'Brien will make his debut as "Tonight Show" host and Will Ferrell is the redheaded funnyman's first guest. "I'm extremely flattered by it," Will told Access Hollywood during an ...

NEW YORK — Conan O'Brien debuts as "Tonight" show host Monday, taking over television's most historic late-night franchise in a transition five years in the making. The network built a new studio for ...

Friday marks the end of Conan O'Brien's seven-month tenure at the helm of the Tonight Show. Though the redheaded host may not have been at the top of his game, losing ratings and eventually the show ...

Widely regarded as one of the best talk show hosts of all time, Conan O'Brien has millions of devoted fans who can't get enough of his sense of humor. As a result, there was a lot of excitement when O ...