Order of cancer-driving mutations affects the chance of tumor development, study shows

The order of cancer-driving mutations—genetic changes—plays an important role in whether tumors in the intestine can develop, ...

Landscape of KRAS mutations and targeted therapies in colorectal cancer mapped in new study

A team of researchers from the Germans Trias i Pujol Research Institute (IGTP) and Institut Català d'Oncologia (ICO) has ...
News-Medical.Net on MSN

AI model ranks genetic variants from severe to mild disease mutations

EVE combines evolutionary insights with human population data to identify damaging genetic mutations, improving variant ...
eLife

Joint profiling of cell morphology and gene expression during in vitro neurodevelopment

Molecular and morphological profiles of developing neurons in vitro uncover the cellular dynamics of human neurodevelopment and related disease.
News-Medical.Net on MSN

Retinal organoids provide a powerful tool to diagnose and study Leber congenital amaurosis

Leber Congenital Amaurosis (LCA) is an inherited retinal disease leading to severe vision impairment from early infancy, affecting 2-3 out of every 100,000 newborns. LCA is caused by variants in ...