A new aldosterone synthase inhibitor added to SGLT2 inhibitors reduces uncontrolled blood pressure in patients with chronic kidney disease, according to the results of a phase 2 trial.

AstraZeneca's aldosterone synthase inhibitor baxdrostat reduced blood pressure by 14 mmHg over 12 weeks, the pharma has said ...

Dr. Aaronson answers the question: 'Aldosterone Antagonist Side Effects?' — -- Question: What are the benefits and side effects of an aldosterone antagonist? Answer: Thanks to research led by Dr.

In a game-changing study, researchers have discovered that excess aldosterone production is a common and unrecognised cause of high blood pressure. Primary aldosteronism is a condition where the ...

Dr. Aaronson answers the question: 'What Is An Aldosterone Antagonist?' — -- Question: What is an aldosterone antagonist, how does it work, and when is it used to treat heart failure? Answer: ...

Type 2 diabetes (T2D) incidence continues to rise among African Americans (AAs). However, it has been observed to plateau among non-Hispanic whites (NHWs). Moreover, T2D-associated mortality and ...

We have reported observing aldosterone breakthrough in the course of relatively long-term treatment with renin–angiotensin (RA) system inhibitors, where the plasma aldosterone concentration (PAC) ...

Increased levels of aldosterone are independently associated with a greater risk of type 2 diabetes, with the effects particularly notable in certain ethnic groups including African Americans and ...

A drug that has been used to slow progression of kidney and cardiovascular disease in people with type 2 diabetes may also help people with chronic kidney disease who do not have diabetes, according ...