Liverpool met the Aslan in their second group game of the campaign on September 30, 2025. It was a largely full-strength team from Slot, though Jeremie Frimpong was playing right-wing and Dominik Szoboszlai was at right-back. In the end, Galatasaray secured a 1-0 home win thanks to a 16th-minute Victor Osimhen penalty.

On a dramatic afternoon in the Premier League, Burnley suffered a heartbreaking 4-3 defeat to Brentford, Everton clinched a 3-2 win over Newcastle and Liverpool scored five against West Ham