Although existing CRISPR-Cas-based imaging methods can target endogenous genomic sequences, their applications are limited by ...

The 2024 Nobel Prize in Physiology or Medicine was awarded to Victor Ambros and Gary Ruvkun for their groundbreaking ...

Over the past decade, several tumor-based predictors of cetuximab efficacy have been identified, yet most function as ...

The Trump administration’s suspension of UCLA’s National Institutes of Health funding jeopardized monumental research. It’s a frightening reality to witness politics impede scientific innovation and ...

Cell culture plates in the Roeder lab where scientists recently studied gene expression in breast cancer. (Credit: Lori ...

Researchers have unveiled the intricate molecular mechanisms governing TCF/LEF-mediated transcription in the canonical Wnt pathway, identifying these proteins as promising therapeutic targets for ...

Replacing APOE4 with APOE2 in adult mice rapidly reshapes brain lipids and gene expression, even after development is ...

A comprehensive review in Current Molecular Pharmacology reveals how TCF/LEF proteins control Wnt signaling through dynamic enhanceosome assembly, post-translational modifications, and isoform ...

New research reveals that women with long COVID show distinct biological disruptions — including gut inflammation, anemia, ...

Overture Life, the global leader in automated IVF and the first company to achieve live births from both robotic fertilization and robotic egg freezing, announced that the company has secured CE Mark ...

Researchers have unveiled the intricate molecular mechanisms governing TCF/LEF-mediated transcription in the canonical Wnt pathway, identifying these ...

Acetylation of lysine residues in the tail domain of histone H3 is well characterized, but lysine residues in the histone globular domain are also acetylated. Histone modifications in globular domain ...