Michael Lew has received funding from the NHMRC. Yesterday’s article by Geoff Cumming, based on a very recent Proceedings of the National Academy of Science paper, argued that “null hypothesis ...

European Journal of Epidemiology, Vol. 25, No. 4 (2010), pp. 225-230 (6 pages) Since its introduction into the biomedical literature, statistical significance testing (abbreviated as SST) caused much ...

A test of statistical significance addresses the question, How likely is a result, assuming the null hypotheses to be true. Randomness, a central assumption underlying commonly used tests of ...

Statistical significance is a critical concept in data analysis and research. In essence, it’s a measure that allows researchers to assess whether the results of an experiment or study are due to ...

I contend that there is a better way to correct the misuse of tests for statistical significance than by dispensing with them altogether (see V. Amrhein et al. Nature 567, 305–307; 2019). The ...

In the middle of the 20 th century, the field of psychology had a problem. In the wake of the Manhattan Project and in the early days of the space race, the so-called “hard sciences” were producing ...

Given a sequencing data set from a single case of rare disease, we want to perform genome-wide tests of the null hypothesis that the variation in the patient was drawn from an unaffected ('healthy') ...

Please provide your email address to receive an email when new articles are posted on . Search engines and chatbots are easy to use. Databases such as gnomAD and ClinVar are comprehensive but come ...