The ratio of posterior wall thickness to the minimum voltage of QRS complexes in limb leads and several parameters derived from electrocardiography could independently predict ATTR-CM. The ratio of ...

Between 21.4% and 57.8% of patients from a real-world ATTR-CM cohort would have been eligible to take part in clinical trials testing disease-modifying therapies. Inclusion and exclusion criteria used ...

The devices are available for patients aged 17 years and older at no extra cost and can be used after receiving training from a healthcare professional. Two new medical devices that will facilitate ...

Awareness of the key symptoms of NF1 can help in early diagnosis. A young male patient was diagnosed with neurofibromatosis type 1 (NF1) after undergoing detailed clinical investigations, according to ...

Barriers to treatment include asparaginase toxicities, limited medical facilities and trained staff, and reduced care access and adherence. Issues of limited access to clinical trials and to expertise ...

The combination strategy of LXH254 and trametinib effectively overcame adaptive and acquired resistance to MEK inhibition. Combined inhibition of B/CRAF and mitogen-activated extracellular ...

Although a pregnant patient may exhibit a favorable response to IVIG treatment in one FNAIT-affected pregnancy, this does not ensure the success of IVIG therapy in subsequent pregnancies. A favorable ...

The AI ECG amyloid algorithm screening tool may provide decision support for clinicians and improve the diagnosis and survival of patients with ATTR-CM. A new study seeks to test an artificial ...

The improvements occurred without any safety concerns, and the trial further indicated that higher total doses enable longer dosing intervals. Umedaptanib pegol, a novel anti-fibroblast growth factor ...

The risks of end-stage renal disease (ESRD) and kidney transplant infection were lower in patients who used SGLT-2 inhibitors at the time of AAV diagnosis. The 5-year survival probability was 90% for ...

NMOSD is a rare autoimmune disorder characterized by inflammation and demyelination of nerves in the central nervous system (CNS), particularly the optic nerves and spinal cord. It typically manifests ...