Plants produce a wide diversity of compounds. Broadly, these are separated into primary metabolites, which are necessary for ...

Spatial metabolomics is transforming our understanding of microbial systems by uncovering the localized molecular dynamics ...

MCM8 deficiency impairs meiotic homologous recombination repair, but the specific role of MCM8 in mitotic germ cells remains poorly understood. This study reveals that MCM8 interacts with helicase ...

Corneal diseases can cause severe visual impairment and even blindness, which have been linked to the interruption of corneal epithelial homeostasis. However, the underlying molecular mechanisms are ...

In this study, using C. elegans and human cell lines, we characterized the physiological effects of thiol reductive stress. Because thiol antioxidants result in the increased expression of rips‐1 ...

The ER membrane protein SELENOT has been previously suggested to be neuroprotective, but its contribution to neuronal pathophysiology has not been thoroughly investigated. This study reports that ...

In our study, we found that ccf-mtDNA exhibits different fragmentomic features, including fragment size, 5′ end base preference, and 5′ end motif diversity from ccf-nDNA. We also observed ...

Recent evidence has revealed that small polypeptides (containing fewer than 100 amino acids) can be translated from noncoding RNAs (ncRNAs), which are usually defined as RNA molecules that do not ...

Motile cells can use and switch between different modes of migration. Here, we use traction force microscopy and fluorescent labeling of actin and myosin to quantify and correlate traction force ...

Correction to: EMBO Molecular Medicine (2024) 16:294–318. https://doi.org/10.1038/s44321-024-00025-1 | Published online 31 January 2024 ...

The class-II transactivator (CIITA) is the master regulator of MHC class-II gene expression and hence the adaptive immune response. Three cell type-specific promoters (pI, pIII, and pIV) are involved ...

EMBO Press is an editorially independent publishing platform for the development of EMBO scientific publications.