May 3, 2023 · High-calorie diet, alcohol, and multiple drug use increase reactive oxygen species (ROS) and cause liver damage. ROS are crucial in the initiation/progression of liver diseases. …

Aug 2, 2017 · Sildenafil functions as a selective and competitive inhibitor of type 5 phosphodiesterases (PDE5) on smooth muscle cells in the penis and pulmonary vasculature, …

Jul 23, 2024 · The purpose of the current investigation was to evaluate sildenafil’s hepatoprotective potential against liver fibrosis in rats that was caused by carbon tetrachloride …

Histopathological examination showed moderate inflammation and marked fibrosis in the liver tissues of male rats after treatment with vardenafil and sildenafil with no changes in the liver of …

LiverTox: Clinical and Research Information on Drug-Induced Liver Injury. 2012 Review Phosphodiesterase type 5 as a pharmacologic target in erectile dysfunction.

Nov 8, 2023 · Can Viagra give you a never-ending erection? Or turn you into a Casanova? A urologist sets the record straight.

Nov 19, 2023 · Acetaminophen (Tylenol) is a common cause of drug-induced liver injury (DILI), and its use is increasing due to the high prevalence of erectile dysfunction (ED) and the …

Sildenafil (Viagra) is used to treat erectile dysfunction (impotence; inability to get or keep an erection) in men. Sildenafil (Liqrev, Revatio) is used to improve the ability to exercise in adults …

Is Sildenafil Hard on the Heart? Sildenafil acts on the blood vessels in your privates, so you may wonder whether it has any worrisome effects on your cardiovascular system as a whole.

Jan 30, 2015 · The researchers found in a mouse model of sepsis that sildenafil, more commonly known as Viagra, induced the liver to produce greater amounts of a protein called cyclic GMP, …